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DOI10.1016/j.marpolbul.2020.111272
Toxicity of a mixture of monoaromatic hydrocarbons (BTX) to a tropical marine microcrustacean
Nascimento M.K.S.; Loureiro S.; Souza M.R.D.R.; Alexandre M.D.R.; Nilin J.
发表日期2020
ISSN0025326X
卷号156
英文摘要This study evaluated the toxicity of benzene, toluene, and xylenes (BTX), isolated and in binary mixtures to Mysidopsis juniae. The organisms were exposed to BTX, and combined effect patterns were predicted by applying the theoretical models of Concentration Addition and Independent Action. According to the LC50 of the isolated compounds, xylene (16.1 ± 2.4 mg L−1) was considered the most toxic, followed by toluene (38.0 ± 5.3 mg L−1) and, lastly, benzene (78.0 ± 2.9 mg L−1). The binary combinations showed deviations from additivity, with exposure to the xylene–benzene mixture presenting as antagonistic, while the xylene–toluene and toluene–benzene mixtures were better explained by a dose ratio deviation, with toluene being responsible for the antagonistic pattern. This study provides new insights into toxicity prediction of a BTX mixture, which adds value to the risk assessment procedure over evaluation of chemical hazards on a case-by-case basis. © 2020 Elsevier Ltd
英文关键词Benzene; Mysid; Survival; Toluene; Xylenes
语种英语
scopus关键词Benzene; Chemical hazards; Risk assessment; Toluene; Toxicity; Tropics; Xylene; Assessment procedure; Benzene , toluene , and xylenes; Binary combinations; Concentration addition; Independent action; Isolated compounds; Monoaromatic hydrocarbon; Toxicity predictions; Binary mixtures; aromatic hydrocarbon; benzene; monoaromatic hydrocarbon derivative; toluene; unclassified drug; xylene; benzene; toluene; xylene; BTEX; concentration (composition); crustacean; risk assessment; toxicity; Article; chemical analysis; Crustacea; ecotoxicity; LC50; marine species; Mysidopsis; Mysidopsis juniae; nonhuman; prediction; risk assessment; theoretical model; toxic concentration; toxicity testing; toxin analysis; tropics; Mysida; Mysidopsis; Benzene; Toluene; Xylenes
来源期刊Marine Pollution Bulletin
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/148891
作者单位Graduate Program in Ecology and Conservation, Federal University of Sergipe, Av. Marechal Rondon s/n, São Cristóvão, Sergipe CEP 49100-000, Brazil; CESAM-Centre for Environmental and Marine Studies and Department of Biology, University of Aveiro, Aveiro, 3810-193, Portugal; Graduate Program in Chemistry, Federal University of Sergipe, Av. Marechal Rondon s/n, São Cristóvão, Sergipe CEP 49100-000, Brazil; Graduate Program in Industrial Biotechnology, Tiradentes University, Av. Murilo Dantas, 300 - Farolândia, Aracaju, Sergipe 49032-490, Brazil; Department of Chemistry, Federal University of Sergipe, Av. Marechal Rondon s/n, São Cristóvão, Sergipe CEP 49100-000, Brazil; Biology Institute, Federal University of Uberlândia, Av. Ceará, s/n Bloco D sala 28, Uberlândia, Minas Gerais 38405-302, Brazil
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Nascimento M.K.S.,Loureiro S.,Souza M.R.D.R.,et al. Toxicity of a mixture of monoaromatic hydrocarbons (BTX) to a tropical marine microcrustacean[J],2020,156.
APA Nascimento M.K.S.,Loureiro S.,Souza M.R.D.R.,Alexandre M.D.R.,&Nilin J..(2020).Toxicity of a mixture of monoaromatic hydrocarbons (BTX) to a tropical marine microcrustacean.Marine Pollution Bulletin,156.
MLA Nascimento M.K.S.,et al."Toxicity of a mixture of monoaromatic hydrocarbons (BTX) to a tropical marine microcrustacean".Marine Pollution Bulletin 156(2020).
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