气候变化领域集成服务门户(CCPortal): Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization

CCPortal

DOI	10.1016/j.marpolbul.2020.111329
	Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization
	Andrade V.C.; Caetano T.; Mendo S.; Oliveira A.J.F.C.D.
发表日期	2020
ISSN	0025326X
卷号	159
英文摘要	Coastal areas with important economic activities have high levels of contamination by metals, pathogenic bacteria, among other contaminants. The emergence of antibiotic-resistant bacteria is a global problem of public health. Carbapenem resistant Enterobacteriaceae (CRE) are a serious threat. The occurrence of carbapenem resistant bacteria was investigated in waters and sediments of a Brazilian coastal area, characterized by high levels of contamination. The samples of water and sediment were collected in two areas of the coast of São Paulo (Brazil). The study involved the characterization of the molecular mechanisms associated with the carbapenem resistance phenotype. No genes were detected for β-lactamases but the absence and/or presence of mutations in outer membrane proteins (OMPs) may justify the detected phenotype. The presented results show the need for further studies that allow a review of the current legislation and the importance of the reevaluation of monitoring policies of these environments. © 2020 Elsevier Ltd
英文关键词	Bacterial resistance; Co-selection; Coastal contamination; Port contamination
语种	英语
scopus关键词	Coastal zones; Economics; Proteins; Antibiotic-resistant bacteria; Economic activities; Enterobacteriaceae; Molecular characterization; Molecular mechanism; Outer membrane protein; Pathogenic bacterium; Resistant bacteria; Bacteria; amoxicillin plus clavulanic acid; ampicillin; aztreonam; cefotaxime; cefoxitin; ceftazidime; ceftriaxone; DNA 16S; ertapenem; fosfomycin; gentamicin; imipenem; meropenem; norfloxacin; outer membrane protein; tetracycline; antiinfective agent; bacterial protein; beta lactamase; carbapenem derivative; antibiotic resistance; bacterium; coastal zone; economic activity; environmental policy; isolation effect; molecular ecology; mutation; phenotype; protein; public health; sediment analysis; sediment pollution; water pollution; water quality; 16S rDNA gene; antibiotic resistance; antibiotic sensitivity; Article; bacterial growth; bacterial strain; bacterium identification; bacterium isolation; Brazil; Budvicia aquatica; carbapenem-resistant Enterobacteriaceae; colony polymerase chain reaction; controlled study; Enterobacter; Enterobacter bugandensis; Escherichia coli; Klebsiella pneumoniae; law; Lemiriorella grimondii; Lemiriorella richardii; minimum inhibitory concentration; mutational analysis; nonhuman; phenotype; Raoultella ornithinolytica; Raoultella plantiocola; seashore; sediment; water pollution; Brazil; Sao Paulo [Brazil]; Bacteria (microorganisms); Enterobacteriaceae; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Brazil; Carbapenem-Resistant Enterobacteriaceae; Carbapenems
来源期刊	Marine Pollution Bulletin
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/148649
作者单位	Departament of Biochemistry and Microbiology, São Paulo State University (UNESP), Rio Claro, Brazil; Marine and Environmental Microbiology Laboratory, São Paulo State University (UNESP), Biosciences Institute, São Vicente, Brazil; CESAM & Department of Biology, University of Aveiro, Aveiro, 3810-193, Portugal
推荐引用方式 GB/T 7714	Andrade V.C.,Caetano T.,Mendo S.,et al. Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization[J],2020,159.
APA	Andrade V.C.,Caetano T.,Mendo S.,&Oliveira A.J.F.C.D..(2020).Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization.Marine Pollution Bulletin,159.
MLA	Andrade V.C.,et al."Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization".Marine Pollution Bulletin 159(2020).