气候变化领域集成服务门户(CCPortal): The Importance of Genetic Redundancy in Evolution

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DOI	10.1016/j.tree.2020.04.009
	The Importance of Genetic Redundancy in Evolution
	Láruson Á.J.; Yeaman S.; Lotterhos K.E.
发表日期	2020
ISSN	0169-5347
英文摘要	Genetic redundancy has been defined in many different ways at different levels of biological organization. Here, we briefly review the general concept of redundancy and focus on the evolutionary importance of redundancy in terms of the number of genotypes that give rise to the same phenotype. We discuss the challenges in determining redundancy empirically, with published experimental examples, and demonstrate the use of the C-score metric to quantify redundancy in evolution studies. We contrast the implicit assumptions of redundancy in quantitative versus population genetic models, show how this contributes to signatures of allele frequency shifts, and highlight how the rapid accumulation of genome-wide association data provides an avenue for further understanding the prevalence and role of redundancy in evolution. © 2020 Elsevier Ltd
语种	英语
来源机构	Trends in Ecology and Evolution
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133909
推荐引用方式 GB/T 7714	Láruson Á.J.,Yeaman S.,Lotterhos K.E.. The Importance of Genetic Redundancy in Evolution[J]. Trends in Ecology and Evolution,2020.
APA	Láruson Á.J.,Yeaman S.,&Lotterhos K.E..(2020).The Importance of Genetic Redundancy in Evolution..
MLA	Láruson Á.J.,et al."The Importance of Genetic Redundancy in Evolution".(2020).