气候变化领域集成服务门户(CCPortal): Endemic infection can shape exposure to novel pathogens: Pathogen co-occurrence networks in the Serengeti lions

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DOI	10.1111/ele.13250
	Endemic infection can shape exposure to novel pathogens: Pathogen co-occurrence networks in the Serengeti lions
	Fountain-Jones N.M.; Packer C.; Jacquot M.; Blanchet F.; Terio K.; Craft M.E.
发表日期	2019
ISSN	1461023X
卷号	22 期号:6
英文摘要	Pathogens are embedded in a complex network of microparasites that can collectively or individually alter disease dynamics and outcomes. Endemic pathogens that infect an individual in the first years of life, for example, can either facilitate or compete with subsequent pathogens thereby exacerbating or ameliorating morbidity and mortality. Pathogen associations are ubiquitous but poorly understood, particularly in wild populations. We report here on 10 years of serological and molecular data in African lions, leveraging comprehensive demographic and behavioural data to test if endemic pathogens shape subsequent infection by epidemic pathogens. We combine network and community ecology approaches to assess broad network structure and characterise associations between pathogens across spatial and temporal scales. We found significant non-random structure in the lion-pathogen co-occurrence network and identified both positive and negative associations between endemic and epidemic pathogens. Our results provide novel insights on the complex associations underlying pathogen co-occurrence networks. © 2019 John Wiley & Sons Ltd/CNRS
英文关键词	Babesia; calicivirus; canine distemper virus; co-infection; community assembly; coronavirus; feline immunodeficiency virus; parvovirus
语种	英语
scopus关键词	Babesia; Caliciviridae; Canine distemper virus; Coronavirus; Feline immunodeficiency virus; Parvovirus; animal; lion; microbiology; parasitology; social behavior; Animals; Lions; Social Behavior
来源期刊	Ecology Letters
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/121091
作者单位	Department of Veterinary Population Medicine, University of Minnesota, 1365 Gortner Avenue, St Paul, MN 55108, United States; Department of Ecology Evolution and Behavior, University of Minnesota, St Paul, MN 55408, United States; INRA, UMR346 EPIA, Epidémiologie des maladies Animales et zoonotiques, Saint-Genès-Champanelle, 63122, France; Département de biologie, Université de Sherbrooke, 2500 Boulevard Université, Sherbrooke, QC J1K 2R1, Canada; Zoological Pathology Program, University of Illinois, Urbana-Champaign, IL, United States
推荐引用方式 GB/T 7714	Fountain-Jones N.M.,Packer C.,Jacquot M.,et al. Endemic infection can shape exposure to novel pathogens: Pathogen co-occurrence networks in the Serengeti lions[J],2019,22(6).
APA	Fountain-Jones N.M.,Packer C.,Jacquot M.,Blanchet F.,Terio K.,&Craft M.E..(2019).Endemic infection can shape exposure to novel pathogens: Pathogen co-occurrence networks in the Serengeti lions.Ecology Letters,22(6).
MLA	Fountain-Jones N.M.,et al."Endemic infection can shape exposure to novel pathogens: Pathogen co-occurrence networks in the Serengeti lions".Ecology Letters 22.6(2019).