气候变化领域集成服务门户(CCPortal): Social immunity modulates competition between coinfecting pathogens

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DOI	10.1111/ele.13458
	Social immunity modulates competition between coinfecting pathogens
	Milutinović B.; Stock M.; Grasse A.V.; Naderlinger E.; Hilbe C.; Cremer S.
发表日期	2020
ISSN	1461023X
卷号	23 期号:3
英文摘要	Coinfections with multiple pathogens can result in complex within-host dynamics affecting virulence and transmission. While multiple infections are intensively studied in solitary hosts, it is so far unresolved how social host interactions interfere with pathogen competition, and if this depends on coinfection diversity. We studied how the collective disease defences of ants – their social immunity – influence pathogen competition in coinfections of same or different fungal pathogen species. Social immunity reduced virulence for all pathogen combinations, but interfered with spore production only in different-species coinfections. Here, it decreased overall pathogen sporulation success while increasing co-sporulation on individual cadavers and maintaining a higher pathogen diversity at the community level. Mathematical modelling revealed that host sanitary care alone can modulate competitive outcomes between pathogens, giving advantage to fast-germinating, thus less grooming-sensitive ones. Host social interactions can hence modulate infection dynamics in coinfected group members, thereby altering pathogen communities at the host level and population level. © 2020 The Authors. Ecology Letters published by CNRS and John Wiley & Sons Ltd
英文关键词	Argentine ants; grooming; host–pathogen interactions; immune-mediated competition; infectious disease; Metarhizium fungus; multiple infections; pathogen competition; pathogen diversity; social insects
语种	英语
scopus关键词	Formicidae; Fungi; Hexapoda; Linepithema humile; Metarhizium; animal; ant; grooming; host pathogen interaction; Metarhizium; social behavior; virulence; Animals; Ants; Grooming; Host-Pathogen Interactions; Metarhizium; Social Behavior; Virulence
来源期刊	Ecology Letters
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/120919
作者单位	IST Austria (Institute of Science and Technology Austria), Am Campus 1, Klosterneuburg, 3400, Austria; Max Planck Institute for Evolutionary Biology, August-Thienemann-Str. 2, Ploen, 24306, Germany
推荐引用方式 GB/T 7714	Milutinović B.,Stock M.,Grasse A.V.,et al. Social immunity modulates competition between coinfecting pathogens[J],2020,23(3).
APA	Milutinović B.,Stock M.,Grasse A.V.,Naderlinger E.,Hilbe C.,&Cremer S..(2020).Social immunity modulates competition between coinfecting pathogens.Ecology Letters,23(3).
MLA	Milutinović B.,et al."Social immunity modulates competition between coinfecting pathogens".Ecology Letters 23.3(2020).