气候变化领域集成服务门户(CCPortal): Allele surfing promotes microbial adaptation from standing variation

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DOI	10.1111/ele.12625
	Allele surfing promotes microbial adaptation from standing variation
	Gralka M.; Stiewe F.; Farrell F.; Möbius W.; Waclaw B.; Hallatschek O.
发表日期	2016
ISSN	1461-023X
EISSN	1461-0248
卷号	19 期号:8
英文摘要	The coupling of ecology and evolution during range expansions enables mutations to establish at expanding range margins and reach high frequencies. This phenomenon, called allele surfing, is thought to have caused revolutions in the gene pool of many species, most evidently in microbial communities. It has remained unclear, however, under which conditions allele surfing promotes or hinders adaptation. Here, using microbial experiments and simulations, we show that, starting with standing adaptive variation, range expansions generate a larger increase in mean fitness than spatially uniform population expansions. The adaptation gain results from ‘soft’ selective sweeps emerging from surfing beneficial mutations. The rate of these surfing events is shown to sensitively depend on the strength of genetic drift, which varies among strains and environmental conditions. More generally, allele surfing promotes the rate of adaptation per biomass produced, which could help developing biofilms and other resource-limited populations to cope with environmental challenges. © 2016 John Wiley & Sons Ltd/CNRS.
英文关键词	Biological invasions; Dynamics of adaptation; Eco-evolutionary feedback; Gene surfing; Genetic drift; Range expansions
学科领域	adaptation; allele; biological model; computer simulation; ecosystem; evolution; genetics; physiology; Saccharomyces cerevisiae; Adaptation, Physiological; Alleles; Biological Evolution; Computer Simulation; Ecosystem; Models, Biological; Saccharomyces cerevisiae
语种	英语
scopus关键词	adaptation; allele; biological model; computer simulation; ecosystem; evolution; genetics; physiology; Saccharomyces cerevisiae; Adaptation, Physiological; Alleles; Biological Evolution; Computer Simulation; Ecosystem; Models, Biological; Saccharomyces cerevisiae
来源期刊	Ecology Letters
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/118517
作者单位	Departments of Physics and Integrative Biology, University of California, Berkeley, CA 94720, United States; Biophysics and Evolutionary Dynamics Group, Max Planck Institute for Dynamics and Self-Organization, Göttingen, 37077, Germany; SUPA School of Physics and Astronomy, The University of Edinburgh, Mayfield Road, Edinburgh, EH9 3JZ, United Kingdom; Centre for Synthetic and Systems Biology, The University of Edinburgh, Edinburgh, United Kingdom
推荐引用方式 GB/T 7714	Gralka M.,Stiewe F.,Farrell F.,et al. Allele surfing promotes microbial adaptation from standing variation[J],2016,19(8).
APA	Gralka M.,Stiewe F.,Farrell F.,Möbius W.,Waclaw B.,&Hallatschek O..(2016).Allele surfing promotes microbial adaptation from standing variation.Ecology Letters,19(8).
MLA	Gralka M.,et al."Allele surfing promotes microbial adaptation from standing variation".Ecology Letters 19.8(2016).