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Nanomedicine enables autophagy-enhanced cancer-cell ferroptosis 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 5
作者:  Yang J.;  Ding L.;  Yu L.;  Wang Y.;  Ge M.;  Jiang Q.;  Chen Y.
收藏  |  浏览/下载：38/0  |  提交时间：2021/09/01
Autophagy  Ferroptosis  Manganese oxide  Mesoporous silica  Trehalose  Tumor therapy  
Fluorescence turn-off magnetic COF composite as a novel nanocarrier for drug loading and targeted delivery 期刊论文
MICROPOROUS AND MESOPOROUS MATERIALS, 2021, 卷号: 311
作者:  Zhao, Kai;  Gong, Peiwei;  Huang, Jie;  Huang, Yan;  Wang, Dandan;  Peng, Jingyi;  Shen, Duyi;  Zheng, Xiaofeng;  You, Jinmao;  Liu, Zhe
收藏  |  浏览/下载：43/0  |  提交时间：2022/04/28
COVALENT ORGANIC FRAMEWORKS  FLUORINATED GRAPHENE  TUMOR  ABSORPTION  PARTICLES  
Immunotherapeutic silk inverse opal particles for post-surgical tumor treatment 期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 5
作者:  Zhang H.;  Liu Y.;  Chen G.;  Wang H.;  Chen C.;  Li M.;  Lu P.;  Zhao Y.
收藏  |  浏览/下载：31/0  |  提交时间：2021/09/01
Biomaterial  Drug delivery  Hydrogel  Inverse opal  Silk fibroin  Tumor immunology  
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Desdín-Micó G.;  Soto-Heredero G.;  Aranda J.F.;  Oller J.;  Carrasco E.;  Gabandé-Rodríguez E.;  Blanco E.M.;  Alfranca A.;  Cussó L.;  Desco M.;  Ibañez B.;  Gortazar A.R.;  Fernández-Marcos P.;  Navarro M.N.;  Hernaez B.;  Alcamí A.;  Baixauli F.;  Mittelbrunn M.
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/28
cardiovascular disease  enzyme activity  gene expression  metabolism  mitochondrial DNA  morbidity  senescence  tumor  Mus  DNA binding protein  mitochondrial protein  mitochondrial transcription factor A  nicotinamide adenine dinucleotide  transcription factor  tumor necrosis factor  animal  cytokine release syndrome  female  fitness  gene deletion  genetics  immunology  inflammation  longevity  male  metabolism  mitochondrion  mouse  multiple chronic conditions  mutant mouse strain  premature aging  T lymphocyte  ultrastructure  Aging, Premature  Animals  Cytokine Release Syndrome  DNA-Binding Proteins  Female  Gene Deletion  Inflammation  Longevity  Male  Mice  Mice, Mutant Strains  Mitochondria  Mitochondrial Proteins  Multimorbidity  NAD  Physical Fitness  T-Lymphocytes  Transcription Factors  Tumor Necrosis Factor-alpha  
Microenvironment mapping via Dexter energy transfer on immune cells 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Geri J.B.;  Oakley J.V.;  Reyes-Robles T.;  Wang T.;  McCarver S.J.;  White C.H.;  Rodriguez-Rivera F.P.;  Parker D.L.;  Hett E.C.;  Fadeyi O.O.;  Oslund R.C.;  MacMillan D.W.C.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
antibody conjugate  carbene  programmed death 1 ligand 1  methane  programmed death 1 ligand 1  antibody  catalysis  catalyst  cell component  detection method  enzyme  enzyme activity  protein  antigen binding  Article  cell membrane  energy transfer  human  immunocompetent cell  immunological synapse  lymphocyte  photocatalysis  priority journal  protein analysis  protein protein interaction  tumor microenvironment  catalysis  chemistry  energy transfer  Jurkat cell line  metabolism  photochemistry  procedures  radiation response  ultraviolet radiation  B7-H1 Antigen  Catalysis  Cell Membrane  Cellular Microenvironment  Energy Transfer  Humans  Jurkat Cells  Lymphocytes  Methane  Photochemical Processes  Protein Interaction Mapping  Protein Interaction Maps  Ultraviolet Rays  
Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  Hoffman D.P.;  Shtengel G.;  Xu C.S.;  Campbell K.R.;  Freeman M.;  Wang L.;  Milkie D.E.;  Pasolli H.A.;  Iyer N.;  Bogovic J.A.;  Stabley D.R.;  Shirinifard A.;  Pang S.;  Peale D.;  Schaefer K.;  Pomp W.;  Chang C.-L.;  Lippincott-Schwartz J.;  Kirchhausen T.;  Solecki D.J.;  Betzig E.;  Hess H.F.
收藏  |  浏览/下载：50/0  |  提交时间：2020/07/28
cell  compartmentalization  cryopreservation  electron microscopy  image resolution  protein  three-dimensional modeling  ultrastructure  article  chromatin  electron microscopy  endoplasmic reticulum  genetic transcription  human cell  mammal cell  nerve cell culture  protein domain  ultrastructure  whole cell  workflow  animal  cell adhesion  cells  Chlorocebus aethiops  cryoelectron microscopy  CV-1 cell line  fluorescence microscopy  freezing  HeLa cell line  human  mouse  procedures  three-dimensional imaging  tumor cell line  ultrastructure  Mammalia  Animals  Cell Adhesion  Cell Line, Tumor  Cells  Chlorocebus aethiops  COS Cells  Cryoelectron Microscopy  Freezing  HeLa Cells  Humans  Imaging, Three-Dimensional  Mice  Microscopy, Fluorescence  
Single-cell transcriptional diversity is a hallmark of developmental potential 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Gulati G.S.;  Sikandar S.S.;  Wesche D.J.;  Manjunath A.;  Bharadwaj A.;  Berger M.J.;  Ilagan F.;  Kuo A.H.;  Hsieh R.W.;  Cai S.;  Zabala M.;  Scheeren F.A.;  Lobo N.A.;  Qian D.;  Yu F.B.;  Dirbas F.M.;  Clarke M.F.;  Newman A.M.
收藏  |  浏览/下载：47/0  |  提交时间：2020/07/28
cell  cell component  developmental biology  experimental study  genetic analysis  tumor  Article  breast cancer  breast carcinogenesis  carcinogenesis  cell differentiation  computer model  embryonic stem cell  gene expression  genetic code  genetic variability  human  in vivo study  nonhuman  phenotype  priority journal  scoring system  single cell RNA seq  upregulation  
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic  
The body's dangerous defenders 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Leslie M.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
alvelestat  avacopan  chemokine receptor CXCR2  danirixin  leukocyte elastase  n [2 (2,3 difluorobenzylthio) 6 (2,3 dihydroxy 1 methylpropoxy) 4 pyrimidinyl] 1 azetidinesulfonamide  nemiralisib  simvastatin  leukocyte elastase inhibitor  antimicrobial activity  apoptosis  cell  enzyme activity  physiological response  ANCA associated vasculitis  Article  autoimmune disease  autoimmunity  bacterial pneumonia  bactericidal activity  bronchiolitis obliterans  drug targeting  extracellular matrix  extracellular trap  hematopoietic stem cell transplantation  human  immunity  immunocompetent cell  infection  inflammation  lung disease  neutrophil  neutrophil chemotaxis  nonhuman  priority journal  risk factor  sepsis  single cell RNA seq  autoimmune disease  chronic obstructive lung disease  clinical trial (topic)  drug effect  enzymology  immunology  lung tumor  neutrophil  Autoimmune Diseases  Clinical Trials as Topic  Humans  Lung Neoplasms  Neutrophils  Proteinase Inhibitory Proteins, Secretory  Pulmonary Disease, Chronic Obstructive  
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Ebright R.Y.;  Lee S.;  Wittner B.S.;  Niederhoffer K.L.;  Nicholson B.T.;  Bardia A.;  Truesdell S.;  Wiley D.F.;  Wesley B.;  Li S.;  Mai A.;  Aceto N.;  Vincent-Jordan N.;  Szabolcs A.;  Chirn B.;  Kreuzer J.;  Comaills V.;  Kalinich M.;  Haas W.;  Ting D.T.;  Toner M.;  Vasudevan S.;  Haber D.A.;  Maheswaran S.;  Micalizzi D.S.
收藏  |  浏览/下载：56/0  |  提交时间：2020/07/28
CRISPR associated protein  epidermal growth factor receptor 2  Ki 67 antigen  ribosome protein  ribosome RNA  transcription factor E2F  ribosome protein  cancer  cell  gene expression  genetic engineering  protein  RNA  tumor  animal experiment  animal model  animal tissue  Article  biogenesis  bioluminescence  breast cancer  cell cycle progression  cell cycle regulation  cell proliferation  circulating tumor cell  controlled study  enzyme activation  epithelial mesenchymal transition  gene expression profiling  genetic transcription  human  human cell  lung metastasis  metastasis  microfluidics  mouse  nonhuman  overall survival  phenotype  priority journal  progression free survival  promoter region  protein expression  protein processing  protein synthesis  proteomics  RNA sequence  transcription regulation  animal  breast tumor  cancer transplantation  CRISPR Cas system  female  gene expression regulation  genetics  pathology  sequence analysis  tumor cell line  tumor embolism  Mus  Animals  Breast Neoplasms  Cell Line, Tumor  CRISPR-Cas Systems  Female  Gene Expression Regulation, Neoplastic  Humans  Mice  Neoplasm Metastasis  Neoplasm Transplantation  Neoplastic Cells, Circulating  Ribosomal Proteins  Sequence Analysis, RNA