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A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Yuan M.;  Wu N.C.;  Zhu X.;  Lee C.-C.D.;  So R.T.Y.;  Lv H.;  Mok C.K.P.;  Wilson I.A.
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/28
angiotensin converting enzyme 2  epitope  neutralizing antibody  virus hemagglutinin  virus spike protein  angiotensin converting enzyme 2  coronavirus receptors  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  neutralizing antibody  spike glycoprotein, SARS-CoV  spike protein, SARS-CoV-2  virus antibody  virus antigen  virus receptor  antibody  antigen  chemical binding  crystal structure  protein  respiratory disease  viral disease  virus  amino terminal sequence  antibody isolation  antigen binding  antigenicity  Article  binding affinity  binding site  conservation biology  controlled study  coronavirus disease 2019  cross reaction  cryoelectron microscopy  crystal structure  enzyme linked immunosorbent assay  epidemic  glycosylation  human  hydrophobicity  immune response  in vitro study  in vivo study  light chain  nonhuman  priority journal  protein conformation  protein domain  protein interaction  protein localization  protein structure  protein targeting  receptor binding  SARS coronavirus  Severe acute respiratory syndrome coronavirus 2  amino acid sequence  antibody affinity  Betacoronavirus  binding site  chemistry  immunology  metabolism  molecular model  SARS coronavirus  X ray crystallography  Coronavirus  SARS coronavirus  Amino Acid Sequence  Antibodies, Neutralizing  Antibodies, Viral  Antibody Affinity  Antigens, Viral  Betacoronavirus  Binding Sites  Cross Reactions  Crystallography, X-Ray  Epitopes  Models, Molecular  Peptidyl-Dipeptidase A  Protein Conformation  Protein Domains  Protein Interaction Domains and Motifs  Receptors, Virus  SARS Virus  Spike Glycoprotein, Coronavirus  
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Wu Y.;  Wang F.;  Shen C.;  Peng W.;  Li D.;  Zhao C.;  Li Z.;  Li S.;  Bi Y.;  Yang Y.;  Gong Y.;  Xiao H.;  Fan Z.;  Tan S.;  Wu G.;  Tan W.;  Lu X.;  Fan C.;  Wang Q.;  Liu Y.;  Zhang C.;  Qi J.;  Gao G.F.;  Gao F.;  Liu L.
收藏  |  浏览/下载：53/0  |  提交时间：2020/07/28
Coronavirus  angiotensin converting enzyme 2  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  monoclonal antibody  neutralizing antibody  virus antibody  virus receptor  animal  chemistry  Coronavirus infection  disease model  human  immunology  isolation and purification  lung  mouse  pandemic  protein domain  serodiagnosis  virology  virus load  virus pneumonia  Animals  Antibodies, Monoclonal  Antibodies, Neutralizing  Antibodies, Viral  Coronavirus Infections  Disease Models, Animal  Humans  Immunodominant Epitopes  Lung  Mice  Neutralization Tests  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Domains  Receptors, Virus  Spike Glycoprotein, Coronavirus  Viral Load  
Synthesis of proteins by automated flow chemistry 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Hartrampf N.;  Saebi A.;  Poskus M.;  Gates Z.P.;  Callahan A.J.;  Cowfer A.E.;  Hanna S.;  Antilla S.;  Schissel C.K.;  Quartararo A.J.;  Ye X.;  Mijalis A.J.;  Simon M.D.;  Loas A.;  Liu S.;  Jessen C.;  Nielsen T.E.;  Pentelute B.L.
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/28
amino acid  cell component  chemistry  instrumentation  peptide  protein  purification  peptide  protein  chemistry  isolation and purification  procedures  protein domain  protein folding  solid phase synthesis  synthesis  Peptides  Protein Domains  Protein Folding  Proteins  Solid-Phase Synthesis Techniques  
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Hervas R.;  Rau M.J.;  Park Y.;  Zhang W.;  Murzin A.G.;  Fitzpatrick J.A.J.;  Scheres S.H.W.;  Si K.
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/28
amyloid protein  cytoplasmic polyadenylation element binding protein  insect protein  protein Orb2  unclassified drug  adult  memory  neurology  protein  substrate  turnover  Article  cryoelectron microscopy  Drosophila  enzyme activity  hydrophilicity  hydrophobicity  memory  nerve cell  nonhuman  priority journal  protein aggregation  protein function  protein isolation  protein processing  protein structure