已选(0)清除
条数/页: 排序方式: |
| Stabilizing electroluminescence color of blue perovskite LEDs via amine group doping 期刊论文 Science Bulletin, 2021 作者: Zhang F.; Song J.; Cai B.; Chen X.; Wei C.; Fang T.; Zeng H. 收藏  |  浏览/下载:168/0  |  提交时间:2021/09/01 Amine-group doping Color stability Hydrogen bond Light-emitting diodes Perovskites Quantum dots |
| Surface hydrogen bond network spatially confined BiOCl oxygen vacancy for photocatalysis 期刊论文 Science Bulletin, 2020, 卷号: 65, 期号: 22 作者: Li H.; Chen S.; Shang H.; Wang X.; Yang Z.; Ai Z.; Zhang L. 收藏  |  浏览/下载:31/0  |  提交时间:2021/09/01 Hydrogen bond NO oxidation Oxygen vacancy Photocatalysis Selectivity |
| Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR 期刊论文 , 2020, 卷号: 367, 期号: 6480 作者: Wingler L.M.; Skiba M.A.; McMahon C.; Staus D.P.; Kleinhenz A.L.W.; Suomivuori C.-M.; Latorraca N.R.; Dror R.O.; Lefkowitz R.J.; Kruse A.C. 收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28 angiotensin 1 receptor beta arrestin G protein coupled receptor biochemistry crystal chemistry crystal structure physiological response protein signaling allosterism alpha helix amino terminal sequence Article binding affinity binding site carboxy terminal sequence conformational transition crystallization hydrogen bond molecular dynamics priority journal protein binding protein conformation protein protein interaction protein stability signal transduction thermostability |
| De novo design of protein logic gates 期刊论文 , 2020, 卷号: 368, 期号: 6486 作者: Chen Z.; Kibler R.D.; Hunt A.; Busch F.; Pearl J.; Jia M.; VanAernum Z.L.; Wicky B.I.M.; Dods G.; Liao H.; Wilken M.S.; Ciarlo C.; Green S.; El-Samad H.; Stamatoyannopoulos J.; Wysocki V.H.; Jewett M.C.; Boyken S.E.; Baker D. 收藏  |  浏览/下载:30/0  |  提交时间:2020/07/28 cell design method gene expression genetic analysis protein activation domain Article binding affinity circular dichroism controlled study de novo design design DNA binding motif enzyme activity genetic transcription human human cell hydrogen bond hydrophobicity mass spectrometry native mass spectrometry nonhuman priority journal protein protein interaction protein structure RNA translation stoichiometry thermodynamics two hybrid system X ray crystallography chemistry genetics logic metabolism protein analysis protein engineering protein processing synthetic biology T lymphocyte yeast HAVCR2 protein, human hepatitis A virus cellular receptor 2 Hepatitis A Virus Cellular Receptor 2 Humans Logic Mass Spectrometry Protein Engineering Protein Interaction Maps Protein Processing, Post-Translational Synthetic Biology T-Lymphocytes Transcription, Genetic Yeasts |
| Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A 期刊论文 , 2020, 卷号: 367, 期号: 6476 作者: Reisberg S.H.; Gao Y.; Walker A.S.; Helfrich E.J.N.; Clardy J.; Baran P.S. 收藏  |  浏览/下载:40/0  |  提交时间:2020/07/28 alkaloid tryptorubin A unclassified drug alkaloid connectivity molecular analysis peptide alkylation Article bioinformatics carbon nuclear magnetic resonance chemical structure chirality cyclization dehydrogenation high performance liquid chromatography hydrogen bond hydrophobicity isomerism nonhuman nuclear magnetic resonance spectroscopy oxidation priority journal protein processing proton nuclear magnetic resonance stereochemistry Streptomyces synthesis X ray crystallography |
| Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved a-ketoamide inhibitors 期刊论文 , 2020, 卷号: 368, 期号: 6489 作者: Zhang L.; Lin D.; Sun X.; Curth U.; Drosten C.; Sauerhering L.; Becker S.; Rox K.; Hilgenfeld R. 收藏  |  浏览/下载:41/0  |  提交时间:2020/07/28 alanine alpha ketoamide inhibitor antivirus agent isoleucine leucine proteinase Severe acute respiratory syndrome coronavirus 2 main protease threonine unclassified drug crystal structure drug enzyme enzyme activity inhibitor reaction kinetics amino acid sequence animal cell animal experiment animal tissue antiviral activity Article catalysis catalytic efficiency controlled study crystal structure dimerization dissociation constant drug clearance drug design drug distribution drug half life drug potency drug protein binding drug solubility drug structure EC50 enzyme inhibition human human cell hydrogen bond hydrophobicity IC50 maximum concentration mean residence time metabolic stability mouse nonhuman priority journal protein structure RNA replication SARS coronavirus Severe acute respiratory syndrome coronavirus 2 viral tropism virus inhibition Coronavirus SARS coronavirus |
| Structure of an active human histone pre-mRNA 3′-end processing machinery 期刊论文 , 2020, 卷号: 367, 期号: 6478 作者: Sun Y.; Zhang Y.; Aik W.S.; Yang X.-C.; Marzluff W.F.; Walz T.; Dominski Z.; Tong L. 收藏  |  浏览/下载:192/0  |  提交时间:2020/07/28 beta lactamase cleavage and polyadenylation specificity factor cleavage and polyadenylation specificity factor 100 cleavage and polyadenylation specificity factor 73 endonuclease histone membrane protein messenger RNA precursor recombinant protein small nuclear ribonucleoprotein small nuclear RNA symplekin U7 small nuclear ribonucleoprotein unclassified drug enzyme activity genetic analysis metazoan protein recombination RNA 3' untranslated region amino terminal sequence Article biochemical analysis carboxy terminal sequence conformational transition controlled study cryoelectron microscopy enzyme active site gene rearrangement genetic analysis hydrogen bond molecular recognition mutagenesis polyadenylation priority journal protein conformation protein protein interaction RNA cleavage RNA processing RNA sequencing Amphora Metazoa |