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Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Guthrie L.M.;  Soma S.;  Yuan S.;  Silva A.;  Zulkifli M.;  Snavely T.C.;  Greene H.F.;  Nunez E.;  Lynch B.;  de Ville C.;  Shanbhag V.;  Lopez F.R.;  Acharya A.;  Petris M.J.;  Kim B.-E.;  Gohil V.M.;  Sacchettini J.C.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
copper  copper zinc superoxide dismutase  cytochrome c oxidase  dopamine beta monooxygenase  elesclomol  monophenol monooxygenase  protein lysine 6 oxidase  copper  cytochrome c oxidase  elesclomol  hydrazine derivative  copper  cytochrome  enzyme  enzyme activity  mitochondrion  mortality  mutation  pathology  rodent  survival  animal cell  animal experiment  animal model  animal tissue  Article  cohort analysis  controlled study  disease severity  drug mechanism  Golgi complex  H9c2(2-1) cell line  in vivo study  male  Menkes syndrome  mitochondrial dynamics  mortality rate  mouse  nerve degeneration  nonhuman  priority journal  secretory pathway  survival rate  animal  brain  cell line  degenerative disease  disease model  drug effect  genetics  knockout mouse  Menkes syndrome  metabolism  mitochondrion  pathology  rat  transport at the cellular level  Murinae  Mus  Animals  Biological Transport  Brain  Cell Line  Copper  Copper Transporter 1  Disease Models, Animal  Electron Transport Complex IV  Hydrazines  Male  Menkes Kinky Hair Syndrome  Mice  Mice, Knockout  Mitochondria  Neurodegenerative Diseases  Rats  
A Bayesian analysis of topographic influences on the presence and severity of beech bark disease 期刊论文
, 2020, 卷号: 472
作者:  Mulder O.;  Sleith R.;  Mulder K.;  Coe N.R.
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/28
Diagnosis  Forestry  Maps  Restoration  Akaike's information criterions  Diameter-at-breast heights  Disease resistance  Environmental factors  Posterior distributions  Predictive models  Slope and aspects  Weighted distance  Disease control  Bayesian analysis  cultivation  deciduous tree  disease resistance  disease severity  disease spread  environmental factor  genetic analysis  topography  Diagnosis  Fagus  Forestry  Maps  Resistance  Restoration  Slope  Trees  Canada  United States  Vermont  Fagus  Fagus grandifolia  
Quantifying losses in productivity by the rust in eucalypt plantations in Brazil 期刊论文
, 2020, 卷号: 468
作者:  Passos dos Santos A.;  Lanças Gomes R.;  Furtado E.L.;  de Souza Passos J.R.
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/28
Forestry  Regression analysis  Scales (weighing instruments)  Biotic factors  Eucalypt plantations  Eucalyptus plantations  Generalized linear model  Gross domestic products  Linear regression models  Non-linear regression  Weighted averages  Productivity  abiotic factor  biotic factor  disease severity  evergreen tree  regression analysis  rust disease  Brazil  Eucalyptus  
Which interventions work best in a pandemic? 期刊论文
, 2020, 卷号: 368, 期号: 6495
作者:  Haushofer J.;  Metcalf C.J.E.
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/28
disease incidence  disease severity  epidemiology  innovation  severe acute respiratory syndrome  viral disease  
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2) 期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:  Li R.;  Pei S.;  Chen B.;  Song Y.;  Zhang T.;  Yang W.;  Shaman J.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
disease prevalence  disease spread  disease transmission  infectious disease  metapopulation  population modeling  viral disease  virus  Article  Bayes theorem  China  conceptual framework  coronavirus disease 2019  data analysis  disease severity  disease transmission  documentation  human  mathematical model  metapopulation  nonhuman  priority journal  Severe acute respiratory syndrome coronavirus 2  travel  validation process  China  Coronavirus  SARS coronavirus  
The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Chinazzi M.;  Davis J.T.;  Ajelli M.;  Gioannini C.;  Litvinova M.;  Merler S.;  Pastore y Piontti A.;  Mu K.;  Rossi L.;  Sun K.;  Viboud C.;  Xiong X.;  Yu H.;  Elizabeth Halloran M.;  Longini I.M.;  Jr.;  Vespignani A.
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/28
disease severity  disease transmission  epidemic  infectivity  metapopulation  quarantine  travel behavior  viral disease  virus  Article  communicable disease control  coronavirus disease 2019  disease transmission  epidemic  human  incidence  incubation time  infection rate  population risk  prevalence  priority journal  quarantine  risk reduction  travel restriction  China  Hubei  Wuhan  Coronavirus  
A rampage through the body 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Wadman M.;  Couzin-Frankel J.;  Kaiser J.;  Matacic C.
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28
blood  brain  brain drain  cell organelle  immune response  infectious disease  protein  viral disease  Article  clinical feature  coronavirus disease 2019  disease severity  disease transmission  human  mortality rate  patient care  patient risk  priority journal  risk factor  Betacoronavirus  blood vessel  brain  Coronavirus infection  female  lung  male  middle aged  multiple organ failure  pandemic  pathogenicity  pathology  virology  virus entry  virus pneumonia  Betacoronavirus  Blood Vessels  Brain  Coronavirus Infections  Female  Humans  Lung  Male  Middle Aged  Multiple Organ Failure  Pandemics  Pneumonia, Viral  Virus Internalization  
Warming affects foliar fungal diseases more than precipitation in a Tibetan alpine meadow 期刊论文
NEW PHYTOLOGIST, 2019, 卷号: 221, 期号: 3, 页码: 1574-1584
作者:  Liu, Xiang;  Ma, Zhiyuan;  Cadotte, Marc W.;  Chen, Fei;  He, Jin-Sheng;  Zhou, Shurong
收藏  |  浏览/下载:26/0  |  提交时间:2019/10/08
altered precipitation  biodiversity  community disease proneness  community pathogen load  ecosystem service  experimental warming  fungal disease severity  global change