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Independent and reproducible hippocampal radiomic biomarkers for multisite Alzheimer's disease: diagnosis, longitudinal progress and biological basis 期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 13
作者:  Zhao K.;  Ding Y.;  Han Y.;  Fan Y.;  Alexander-Bloch A.F.;  Han T.;  Jin D.;  Liu B.;  Lu J.;  Song C.;  Wang P.;  Wang D.;  Wang Q.;  Xu K.;  Yang H.;  Yao H.;  Zheng Y.;  Yu C.;  Zhou B.;  Zhang X.;  Zhou Y.;  Jiang T.;  Zhang X.;  Liu Y.;  Alzheimer's Disease Neuroimaging Initiative;  Multi-Center Alzheimer Disease Imaging Consortium
收藏  |  浏览/下载：47/0  |  提交时间：2021/09/01
Biological basis  Brain biomarker  Hippocampal radiomic features  Independent cross-validation  Multisite Alzheimer's disease MRI  
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Guthrie L.M.;  Soma S.;  Yuan S.;  Silva A.;  Zulkifli M.;  Snavely T.C.;  Greene H.F.;  Nunez E.;  Lynch B.;  de Ville C.;  Shanbhag V.;  Lopez F.R.;  Acharya A.;  Petris M.J.;  Kim B.-E.;  Gohil V.M.;  Sacchettini J.C.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
copper  copper zinc superoxide dismutase  cytochrome c oxidase  dopamine beta monooxygenase  elesclomol  monophenol monooxygenase  protein lysine 6 oxidase  copper  cytochrome c oxidase  elesclomol  hydrazine derivative  copper  cytochrome  enzyme  enzyme activity  mitochondrion  mortality  mutation  pathology  rodent  survival  animal cell  animal experiment  animal model  animal tissue  Article  cohort analysis  controlled study  disease severity  drug mechanism  Golgi complex  H9c2(2-1) cell line  in vivo study  male  Menkes syndrome  mitochondrial dynamics  mortality rate  mouse  nerve degeneration  nonhuman  priority journal  secretory pathway  survival rate  animal  brain  cell line  degenerative disease  disease model  drug effect  genetics  knockout mouse  Menkes syndrome  metabolism  mitochondrion  pathology  rat  transport at the cellular level  Murinae  Mus  Animals  Biological Transport  Brain  Cell Line  Copper  Copper Transporter 1  Disease Models, Animal  Electron Transport Complex IV  Hydrazines  Male  Menkes Kinky Hair Syndrome  Mice  Mice, Knockout  Mitochondria  Neurodegenerative Diseases  Rats  
Meet the psychobiome 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Pennisi E.
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4 aminobutyric acid  antibiotic agent  dopamine  kynurenine  probiotic agent  queuine  serotonin  psychotropic agent  bacterium  biome  drug  microbial activity  nervous system disorder  allergy  Alzheimer disease  antimicrobial therapy  anxiety disorder  archaeon  Article  autism  bacterium culture  Bacteroides  blood brain barrier  blood vessel  brain disease  clinical effectiveness  constipation  depression  drug use  enteroendocrine cell  enteropathy  entrepreneurship  epilepsy  fecal microbiota transplantation  feces analysis  Food and Drug Administration  fungus  genomics  human  insomnia  intestine flora  irritable colon  mammal cell  microbiology  microbiome  nerve cell  nervous system  nervous system development  neurologic disease  nonhuman  obesity  pain threshold  Parkinson disease  physician  priority journal  psychobiome  psychological aspect  psychological well-being  schizophrenia  scientist  United States  vagus nerve  virus  animal  bacterium  chemistry  drug development  intestine flora  isolation and purification  metabolism  microbiology  physiology  procedures  Animals  Bacteria  Drug Discovery  Gastrointestinal Microbiome  Humans  Nervous System Diseases  Psychotropic Drugs  
The genetic architecture of the human cerebral cortex 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Grasby K.L.;  Jahanshad N.;  Painter J.N.;  Colodro-Conde L.;  Bralten J.;  Hibar D.P.;  Lind P.A.;  Pizzagalli F.;  Ching C.R.K.;  McMahon M.A.B.;  Shatokhina N.;  Zsembik L.C.P.;  Thomopoulos S.I.;  Zhu A.H.;  Strike L.T.;  Agartz I.;  Alhusaini S.;  Almeida M.A.A.;  Alnæs D.;  Amlien I.K.;  Andersson M.;  Ard T.;  Armstrong N.J.;  Ashley-Koch A.;  Atkins J.R.;  Bernard M.;  Brouwer R.M.;  Buimer E.E.L.;  Bülow R.;  Bürger C.;  Cannon D.M.;  Chakravarty M.;  Chen Q.;  Cheung J.W.;  Couvy-Duchesne B.;  Dale A.M.;  Dalvie S.;  de Araujo T.K.;  de Zubicaray G.I.;  de Zwarte S.M.C.;  den Braber A.;  Doan N.T.;  Dohm K.;  Ehrlich S.;  Engelbrecht H.-R.;  Erk S.;  Fan C.C.;  Fedko I.O.;  Foley S.F.;  Ford J.M.;  Fukunaga M.;  Garrett M.E.;  Ge T.;  Giddaluru S.;  Goldman A.L.;  Green M.J.;  Groenewold N.A.;  Grotegerd D.;  Gurholt T.P.;  Gutman B.A.;  Hansell N.K.;  Harris M.A.;  Harrison M.B.;  Haswell C.C.;  Hauser M.;  Herms S.;  Heslenfeld D.J.;  Ho N.F.;  Hoehn D.;  Hoffmann P.;  Holleran L.;  Hoogman M.;  Hottenga J.-J.;  Ikeda M.;  Janowitz D.;  Jansen I.E.;  Jia T.;  Jockwitz C.;  Kanai R.;  Karama S.;  Kasperaviciute D.;  Kaufmann T.;  Kelly S.;  Kikuchi M.;  Klein M.;  Knapp M.;  Knodt A.R.;  Krämer B.;  Lam M.;  Lancaster T.M.;  Lee P.H.;  Lett T.A.;  Lewis L.B.;  Lopes-Cendes I.;  Luciano M.;  Macciardi F.;  Marquand A.F.;  Mathias S.R.;  Melzer T.R.;  Milaneschi Y.;  Mirza-Schreiber N.;  Moreira J.C.V.;  Mühleisen T.W.;  Müller-Myhsok B.;  Najt P.;  Nakahara S.;  Nho K.;  Olde Loohuis L.M.;  Orfanos D.P.;  Pearson J.F.;  Pitcher T.L.;  Pütz B.;  Quidé Y.;  Ragothaman A.;  Rashid F.M.;  Reay W.R.;  Redlich R.;  Reinbold C.S.;  Repple J.;  Richard G.;  Riedel B.C.;  Risacher S.L.;  Rocha C.S.;  Mota N.R.;  Salminen L.;  Saremi A.;  Saykin A.J.;  Schlag F.;  Schmaal L.;  Schofield P.R.;  Secolin R.;  Shapland C.Y.;  Shen L.;  Shin J.;  Shumskaya E.;  Sønderby I.E.;  Sprooten E.;  Tansey K.E.;  Teumer A.;  Thalamuthu A.;  Tordesillas-Gutiérrez D.;  Turner J.A.;  Uhlmann A.;  Vallerga C.L.;  van der Meer D.;  van Donkelaar M.M.J.;  van Eijk L.;  van Erp T.G.M.;  van Haren N.E.M.;  van Rooij D.;  van Tol M.-J.;  Veldink J.H.;  Verhoef E.;  Walton E.;  Wang M.;  Wang Y.;  Wardlaw J.M.;  Wen W.;  Westlye L.T.;  Whelan C.D.;  Witt S.H.;  Wittfeld K.;  Wolf C.;  Wolfers T.;  Wu J.Q.;  Yasuda C.L.;  Zaremba D.;  Zhang Z.;  Zwiers M.P.;  Artiges E.;  Assareh A.A.;  Ayesa-Arriola R.;  Belger A.;  Brandt C.L.;  Brown G.G.;  Cichon S.;  Curran J.E.;  Davies G.E.;  Degenhardt F.;  Dennis M.F.;  Dietsche B.;  Djurovic S.;  Doherty C.P.;  Espiritu R.;  Garijo D.;  Gil Y.;  Gowland P.A.;  Green R.C.;  Häusler A.N.;  Heindel W.;  Ho B.-C.;  Hoffmann W.U.;  Holsboer F.;  Homuth G.;  Hosten N.;  Jack C.R.;  Jang M.;  Jansen A.;  Kimbrel N.A.;  Kolskår K.;  Koops S.;  Krug A.;  Lim K.O.;  Luykx J.J.;  Mathalon D.H.;  Mather K.A.;  Mattay V.S.;  Matthews S.;  van Son J.M.;  McEwen S.C.;  Melle I.;  Morris D.W.;  Mueller B.A.;  Nauck M.;  Nordvik J.E.;  Nöthen M.M.;  O'Leary D.S.;  Opel N.;  Martinot M.-L.P.;  Bruce Pike G.;  Preda A.;  Quinlan E.B.;  Rasser P.E.;  Ratnakar V.;  Reppermund S.;  Steen V.M.;  Tooney P.A.;  Torres F.R.;  Veltman D.J.;  Voyvodic J.T.;  Whelan R.;  White T.;  Yamamori H.;  Adams H.H.H.;  Bis J.C.;  Debette S.;  Decarli C.;  Fornage M.;  Gudnason V.;  Hofer E.;  Arfan Ikram M.;  Launer L.;  Longstreth W.T.;  Lopez O.L.;  Mazoyer B.;  Mosley T.H.;  Roshchupkin G.V.;  Satizabal C.L.;  Schmidt R.;  Seshadri S.;  Yang Q.;  Alvim M.K.M.;  Ames D.;  Anderson T.J.;  Andreassen O.A.;  Arias-Vasquez A.;  Bastin M.E.;  Baune B.T.;  Beckham J.C.;  Blangero J.;  Boomsma D.I.;  Brodaty H.;  Brunner H.G.;  Buckner R.L.;  Buitelaar J.K.;  Bustillo J.R.;  Cahn W.;  Cairns M.J.;  Calhoun V.;  Carr V.J.;  Caseras X.;  Caspers S.;  Cavalleri G.L.;  Cendes F.;  Corvin A.;  Crespo-Facorro B.;  Dalrymple-Alford J.C.;  Dannlowski U.;  de Geus E.J.C.;  Deary I.J.;  Delanty N.;  Depondt C.;  Desrivières S.;  Donohoe G.;  Espeseth T.;  Fernández G.;  Fisher S.E.;  Flor H.;  Forstner A.J.;  Francks C.;  Franke B.;  Glahn D.C.;  Gollub R.L.;  Grabe H.J.;  Gruber O.;  Håberg A.K.;  Hariri A.R.;  Hartman C.A.;  Hashimoto R.;  Heinz A.;  Henskens F.A.;  Hillegers M.H.J.;  Hoekstra P.J.;  Holmes A.J.;  Elliot Hong L.;  Hopkins W.D.;  Hulshoff Pol H.E.;  Jernigan T.L.;  Jönsson E.G.;  Kahn R.S.;  Kennedy M.A.;  Kircher T.T.J.;  Kochunov P.;  Kwok J.B.J.;  Le Hellard S.;  Loughland C.M.;  Martin N.G.;  Martinot J.-L.;  McDonald C.;  McMahon K.L.;  Meyer-Lindenberg A.;  Michie P.T.;  Morey R.A.;  Mowry B.;  Nyberg L.;  Oosterlaan J.;  Ophoff R.A.;  Pantelis C.;  Paus T.;  Pausova Z.;  Penninx B.W.J.H.;  Polderman T.J.C.;  Posthuma D.;  Rietschel M.;  Roffman J.L.;  Rowland L.M.;  Sachdev P.S.;  Sämann P.G.;  Schall U.;  Schumann G.;  Scott R.J.;  Sim K.;  Sisodiya S.M.;  Smoller J.W.;  Sommer I.E.;  Pourcain B.S.;  Stein D.J.;  Toga A.W.;  Trollor J.N.;  van der Wee N.J.A.;  van't Ent D.;  Völzke H.;  Walter H.;  Weber B.;  Weinberger D.R.;  Wright M.J.;  Zhou J.;  Stein J.L.;  Thompson P.M.;  Medland S.E.;  Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group
收藏  |  浏览/下载：62/0  |  提交时间：2020/07/28
brain  genetic analysis  meta-analysis  resonance  signaling  surface area  Article  bioinformatics  brain cortex  brain function  brain region  brain tissue  cortical thickness (brain)  educational status  evidence based medicine  gene control  gene locus  genetic association  genetic correlation  genetic variability  genome-wide association study  human  human genetics  priority journal  surface area  tissue structure  Wnt signaling  anatomy and histology  attention deficit disorder  brain cortex  brain mapping  cognition  genetic variation  genetics  meta analysis  nuclear magnetic resonance imaging  organ size  Parkinson disease  Attention Deficit Disorder with Hyperactivity  Brain Mapping  Cerebral Cortex  Cognition  Genetic Loci  Genetic Variation  Genome-Wide Association Study  Humans  Magnetic Resonance Imaging  Organ Size  Parkinson Disease  
Chromatin accessibility dynamics in a model of human forebrain development 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Trevino A.E.;  Sinnott-Armstrong N.;  Andersen J.;  Yoon S.-J.;  Huber N.;  Pritchard J.K.;  Chang H.Y.;  Greenleaf W.J.;  Pașca S.P.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
brain  cell component  developmental biology  developmental stage  disease  genetic analysis  nervous system disorder  Article  brain cortex  brain development  brain nerve cell  brain tissue  cell differentiation  cell migration  chromatin  controlled study  environmental factor  fluorescence activated cell sorting  forebrain  GABAergic system  glia cell  heredity  high throughput sequencing  human  human cell  human tissue  pluripotent stem cell  priority journal  RNA isolation  RNA sequence  RNA sequencing  
A rampage through the body 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Wadman M.;  Couzin-Frankel J.;  Kaiser J.;  Matacic C.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
blood  brain  brain drain  cell organelle  immune response  infectious disease  protein  viral disease  Article  clinical feature  coronavirus disease 2019  disease severity  disease transmission  human  mortality rate  patient care  patient risk  priority journal  risk factor  Betacoronavirus  blood vessel  brain  Coronavirus infection  female  lung  male  middle aged  multiple organ failure  pandemic  pathogenicity  pathology  virology  virus entry  virus pneumonia  Betacoronavirus  Blood Vessels  Brain  Coronavirus Infections  Female  Humans  Lung  Male  Middle Aged  Multiple Organ Failure  Pandemics  Pneumonia, Viral  Virus Internalization  
Brain diseases in changing climate 期刊论文
ENVIRONMENTAL RESEARCH, 2019, 卷号: 177
作者:  Ruszkiewicz, Joanna A.;  Tinkov, Alexey A.;  Skalny, Anatoly, V;  Siokas, Vasileios;  Dardiotis, Efthimios;  Tsatsakis, Aristidis;  Bowman, Aaron B.;  da Rocha, Joao B. T.;  Aschner, Michael
收藏  |  浏览/下载：31/0  |  提交时间：2019/10/08
Climate change  Environment  Health  Brain disease