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Paternal age negatively affects sperm production of the progeny
期刊论文
Ecology Letters, 2021, 卷号: 24, 期号: 4
作者:
Vuarin P.
;
Lesobre L.
;
Levêque G.
;
Saint Jalme M.
;
Lacroix F.
;
Hingrat Y.
;
Sorci G.
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/09/01
Ageing
ejaculate quality
male gametes
offspring phenotype
paternal age
post-copulatory sexual selection
reproductive senescence
Combining multiple tactics over time for cost-effective eradication of invading insect populations
期刊论文
Ecology Letters, 2021, 卷号: 24, 期号: 2
作者:
Lampert A.
;
Liebhold A.M.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/09/01
Bioeconomic
extinction
gypsy moth
insecticide
invasion
management
mating disruption
model
optimisation
sterile male
Absence of murine CFAP61 causes male infertility due to multiple morphological abnormalities of the flagella
期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 10
作者:
Huang T.
;
Yin Y.
;
Liu C.
;
Li M.
;
Yu X.
;
Wang X.
;
Zhang H.
;
Muhammad T.
;
Gao F.
;
Li W.
;
Chen Z.-J.
;
Liu H.
;
Ma J.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/09/01
Cfap61
Flagellum development
Male infertility
Multiple morphological abnormalities of the flagella (MMAF)
Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China
期刊论文
, 2020, 卷号: 368, 期号: 6498
作者:
Zhang J.
;
Litvinova M.
;
Liang Y.
;
Wang Y.
;
Wang W.
;
Zhao S.
;
Wu Q.
;
Merler S.
;
Viboud C.
;
Vespignani A.
;
Ajelli M.
;
Yu H.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
adolescent
adult
age
aged
behavior
Betacoronavirus
child
China
communicable disease control
contact examination
Coronavirus infection
disease predisposition
epidemic
female
human
infant
male
middle aged
pandemic
preschool child
school
theoretical model
virus pneumonia
workplace
young adult
Adolescent
Adult
Age Factors
Aged
Behavior
Betacoronavirus
Child
Child, Preschool
China
Communicable Disease Control
Contact Tracing
Coronavirus Infections
Disease Outbreaks
Disease Susceptibility
Female
Humans
Infant
Male
Middle Aged
Models, Theoretical
Pandemics
Pneumonia, Viral
Schools
Workplace
Young Adult
Does socioeconomic status moderate the political divide on climate change? The roles of education, income, and individualism
期刊论文
Global Environmental Change, 2020, 卷号: 60
作者:
Ballew M.T.
;
Pearson A.R.
;
Goldberg M.H.
;
Rosenthal S.A.
;
Leiserowitz A.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/09/01
Climate change
Conservative white male effect
Education
Income
Individualism
Polarization
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Dai W.
;
Zhang B.
;
Jiang X.-M.
;
Su H.
;
Li J.
;
Zhao Y.
;
Xie X.
;
Jin Z.
;
Peng J.
;
Liu F.
;
Li C.
;
Li Y.
;
Bai F.
;
Wang H.
;
Cheng X.
;
Cen X.
;
Hu S.
;
Yang X.
;
Wang J.
;
Liu X.
;
Xiao G.
;
Jiang H.
;
Rao Z.
;
Zhang L.-K.
;
Xu Y.
;
Yang H.
;
Liu H.
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/28
aldehyde
antimicrobial activity
drug
enzyme activity
infectivity
inhibitor
reaction kinetics
viral disease
Coronavirus
SARS coronavirus
3C-like proteinase, Coronavirus
antivirus agent
cysteine proteinase
viral protein
animal
Betacoronavirus
chemical structure
chemistry
Chlorocebus aethiops
Coronavirus infection
dog
drug design
drug effect
enzyme active site
enzymology
female
human
male
mouse
pandemic
preclinical study
protein tertiary structure
Sprague Dawley rat
toxicity testing
Vero cell line
virus pneumonia
Animals
Antiviral Agents
Betacoronavirus
Catalytic Domain
Chlorocebus aethiops
Coronavirus Infections
Cysteine Endopeptidases
Dogs
Drug Design
Drug Evaluation, Preclinical
Female
Humans
Male
Mice
Molecular Structure
Pandemics
Pneumonia, Viral
Protein Structure, Tertiary
Rats, Sprague-Dawley
Toxicity Tests
Vero Cells
Viral Nonstructural Proteins
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Desdín-Micó G.
;
Soto-Heredero G.
;
Aranda J.F.
;
Oller J.
;
Carrasco E.
;
Gabandé-Rodríguez E.
;
Blanco E.M.
;
Alfranca A.
;
Cussó L.
;
Desco M.
;
Ibañez B.
;
Gortazar A.R.
;
Fernández-Marcos P.
;
Navarro M.N.
;
Hernaez B.
;
Alcamí A.
;
Baixauli F.
;
Mittelbrunn M.
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/28
cardiovascular disease
enzyme activity
gene expression
metabolism
mitochondrial DNA
morbidity
senescence
tumor
Mus
DNA binding protein
mitochondrial protein
mitochondrial transcription factor A
nicotinamide adenine dinucleotide
transcription factor
tumor necrosis factor
animal
cytokine release syndrome
female
fitness
gene deletion
genetics
immunology
inflammation
longevity
male
metabolism
mitochondrion
mouse
multiple chronic conditions
mutant mouse strain
premature aging
T lymphocyte
ultrastructure
Aging, Premature
Animals
Cytokine Release Syndrome
DNA-Binding Proteins
Female
Gene Deletion
Inflammation
Longevity
Male
Mice
Mice, Mutant Strains
Mitochondria
Mitochondrial Proteins
Multimorbidity
NAD
Physical Fitness
T-Lymphocytes
Transcription Factors
Tumor Necrosis Factor-alpha
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
Widespread receptor-driven modulation in peripheral olfactory coding
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Xu L.
;
Li W.
;
Voleti V.
;
Zou D.-J.
;
Hillman E.M.C.
;
Firestein S.
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/28
antagonism
cell component
detection method
odor
olfaction
protein
animal cell
animal experiment
article
excitation
high throughput analysis
male
microscopy
mouse
nonhuman
odor
olfactory epithelium
olfactory receptor neuron
animal
confocal microscopy
innervation
mutant mouse strain
olfactory mucosa
physiology
single cell analysis
acetophenone
acetophenone derivative
benzyl acetate
benzyl derivative
citral
fragrance
Acetophenones
Acyclic Monoterpenes
Animals
Benzyl Compounds
Mice
Mice, Mutant Strains
Microscopy, Confocal
Odorants
Olfactory Mucosa
Olfactory Receptor Neurons
Single-Cell Analysis
Smell
Transcription factor AP2 controls cnidarian germ cell induction
期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:
DuBuc T.Q.
;
Schnitzler C.E.
;
Chrysostomou E.
;
McMahon E.T.
;
Febrimarsa
;
Gahan J.M.
;
Buggie T.
;
Gornik S.G.
;
Hanley S.
;
Barreira S.N.
;
Gonzalez P.
;
Baxevanis A.D.
;
Frank U.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/28
transcription factor
transcription factor AP2
unclassified drug
clonal organism
gene expression
germ cell
invertebrate
physiological response
protein
adult
Article
cell fate
Cnidaria
embryo
female
genotype
germ cell
gonad development
Hydractinia symbiolongicarpus
male
nonhuman
phenotype
priority journal
protein expression
wild type
Animalia
Bilateria
Hydractinia symbiolongicarpus
Mammalia