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Status of acute systemic toxicity testing requirements and data uses by US regulatory agencies 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2018, 卷号: 94, 页码: 183-196
作者:  Strickland, Judy;  Clippinger, Amy J.;  Brown, Jeffrey;  Allen, David;  Jacobs, Abigail;  Matheson, Joanna;  Lowit, Anna;  Reinke, Emily N.;  Johnson, Mark S.;  Quinn, Michael J., Jr.;  Mattie, David;  Fitzpatrick, Suzanne C.;  Ahir, Surender;  Kleinstreuer, Nicole;  Casey, Warren
收藏  |  浏览/下载:26/0  |  提交时间:2019/05/04
Human relevance of rodent liver tumors: Key insights from a Toxicology Forum workshop on nongenotoxic modes of action 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2018, 卷号: 92, 页码: 1-7
作者:  Felter, Susan P.;  Foreman, Jennifer E.;  Boobis, Alan;  Corton, J. Christopher;  Doi, Adriana M.;  Flowers, Lynn;  Goodman, Jay;  Haber, Lynne T.;  Jacobs, Abigail;  Klaunig, James E.;  Lynch, Angela M.;  Moggs, Jonathan;  Pandiri, Arun
收藏  |  浏览/下载:34/0  |  提交时间:2019/05/04
Prediction of skin sensitization potency using machine learning approaches 期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2017, 卷号: 37, 期号: 7, 页码: 792-805
作者:  Zang, Qingda;  Paris, Michael;  Lehmann, David M.;  Bell, Shannon;  Kleinstreuer, Nicole;  Allen, David;  Matheson, Joanna;  Jacobs, Abigail;  Casey, Warren;  Strickland, Judy
收藏  |  浏览/下载:30/0  |  提交时间:2019/05/04
Multivariate models for prediction of human skin sensitization hazard 期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2017, 卷号: 37, 期号: 3, 页码: 347-360
作者:  Strickland, Judy;  Zang, Qingda;  Paris, Michael;  Lehmann, David M.;  Allen, David;  Choksi, Neepa;  Matheson, Joanna;  Jacobs, Abigail;  Casey, Warren;  Kleinstreuer, Nicole
收藏  |  浏览/下载:42/0  |  提交时间:2019/05/04
Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their re-evaluation 期刊论文
CRITICAL REVIEWS IN TOXICOLOGY, 2017, 卷号: 47, 期号: 8, 页码: 705-727
作者:  Boobis, Alan;  Brown, Paul;  Cronin, Mark Timothy David;  Edwards, James;  Galli, Corrado Lodovico;  Goodman, Jay;  Jacobs, Abigail;  Kirkland, David;  Luijten, Mirjam;  Marsaux, Cyril;  Martin, Matthew;  Yang, Chihae;  Hollnagel, Heli Miriam
收藏  |  浏览/下载:21/0  |  提交时间:2019/05/04
Integrated decision strategies for skin sensitization hazard 期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2016, 卷号: 36, 期号: 9, 页码: 1150-1162
作者:  Strickland, Judy;  Zang, Qingda;  Kleinstreuer, Nicole;  Paris, Michael;  Lehmann, David M.;  Choksi, Neepa;  Matheson, Joanna;  Jacobs, Abigail;  Lowit, Anna;  Allen, David;  Casey, Warren
收藏  |  浏览/下载:41/0  |  提交时间:2019/05/04
A New Path Forward: The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and National Toxicology Program's Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) 期刊论文
JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE, 2015, 卷号: 54, 期号: 2, 页码: 170-173
作者:  Casey, Warren;  Jacobs, Abigail;  Maull, Elizabeth;  Matheson, Joanna;  Clarke, Carol;  Lowit, Anna
收藏  |  浏览/下载:27/0  |  提交时间:2019/05/04
Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator 期刊论文
CRITICAL REVIEWS IN TOXICOLOGY, 2014, 卷号: 44, 期号: 1, 页码: 64-82
作者:  Elcombe, Clifford R.;  Peffer, Richard C.;  Wolf, Douglas C.;  Bailey, Jason;  Bars, Remi;  Bell, David;  Cattley, Russell C.;  Ferguson, Stephen S.;  Geter, David;  Goetz, Amber;  Goodman, Jay I.;  Hester, Susan;  Jacobs, Abigail;  Omiecinski, Curtis J.;  Schoeny, Rita;  Xie, Wen;  Lake, Brian G.
收藏  |  浏览/下载:28/0  |  提交时间:2019/05/04
Developing Microphysiological Systems for Use as Regulatory Tools - Challenges and Opportunities 期刊论文
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2014, 卷号: 31, 期号: 3, 页码: 364-367
作者:  Andersen, Melvin E.;  Betts, Kellyn;  Dragan, Yvonne;  Fitzpatrick, Suzanne;  Goodman, Jesse L.;  Hartung, Thomas;  Himmelfarb, Jonathan;  Ingber, Donald E.;  Jacobs, Abigail;  Kavlock, Robert;  Kolaja, Kyle;  Stevens, James L.;  Tagle, Dan;  Taylor, D. Lansing;  Throckmorton, Douglas
收藏  |  浏览/下载:29/0  |  提交时间:2019/05/04
EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity 期刊论文
TOXICOLOGICAL SCIENCES, 2013, 卷号: 135, 期号: 2, 页码: 277-291
作者:  Shen, Jie;  Xu, Lei;  Fang, Hong;  Richard, Ann M.;  Bray, Jeffrey D.;  Judson, Richard S.;  Zhou, Guangxu;  Colatsky, Thomas J.;  Aungst, Jason L.;  Teng, Christina;  Harris, Steve C.;  Ge, Weigong;  Dai, Susie Y.;  Su, Zhenqiang;  Jacobs, Abigail C.;  Harrouk, Wafa;  Perkins, Roger;  Tong, Weida;  Hong, Huixiao
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/04