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| Investigating antiviral activities of iodine-conjugated organic agents against major viruses infecting pepper in Korea 期刊论文 CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE, 2024, 卷号: 11, 期号: 1 收藏  |  浏览/下载:0/0  |  提交时间:2024/06/11 |
| Efficacy of Nirmatrelvir-Ritonavir versus Azvudine for COVID-19 Treatment in Tibet: A Retrospective Study 期刊论文 INFECTION AND DRUG RESISTANCE, 2023, 卷号: 16 作者: Zhao, Xiang; Cheng, Yuan; Zhang, Meng; Qianda, Bianba; Zhouma, Baima; Yangzhen, Bianba; Zheng, Yao; Zhang, Shuo; Zhao, Huiying 收藏  |  浏览/下载:1/0  |  提交时间:2024/03/01 nirmatrelvir-ritonavir azvudine COVID-19 clinical outcome high altitude |
| Science academies publish statements on primary concerns for international action ahead of the G7 summit 科技资讯 2022 收藏  |  浏览/下载:9/0  |  提交时间:2022/06/01 |
| Review on Meteorological and Air Quality Factors Affecting the COVID-19 Pandemic 科技报告 , 2021 作者: [unavailable] Adobe PDF(1972Kb)  |  收藏  |  浏览/下载:26/2  |  提交时间:2021/11/24 |
| Drugs used to treat HIV and flu can have detrimental impact on crops 科技资讯 2021 收藏  |  浏览/下载:1/0  |  提交时间:2021/01/29 |
| The Sw5a gene confers resistance to ToLCNDV and triggers an HR response after direct AC4 effector recognition 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33 作者: Sharma N.; Sahu P.P.; Prasad A.; Muthamilarasan M.; Waseem M.; Khan Y.; Thakur J.K.; Chakraborty S.; Prasad M. 收藏  |  浏览/下载:52/0  |  提交时间:2021/11/25 |
| miR-122-based therapies select for three distinct resistance mechanisms based on alterations in RNA structure 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33 作者: Chahal J.; Gebert L.F.R.; Camargo C.; MacRae I.J.; Sagan S.M. 收藏  |  浏览/下载:12/0  |  提交时间:2021/11/25 |
| Structural basis for strand-transfer inhibitor binding to HIV intasomes 期刊论文 , 2020, 卷号: 367, 期号: 6479 作者: Passos D.O.; Li M.; Jóźwik I.K.; Zhao X.Z.; Santos-Martins D.; Yang R.; Smith S.J.; Jeon Y.; Forli S.; Hughes S.H.; Burke T.R.; Jr.; Craigie R.; Lyumkis D. 收藏  |  浏览/下载:19/0  |  提交时间:2020/07/28 bictegravir nucleoprotein protein intasome unclassified drug viral protein bictegravir fused heterocyclic rings integrase integrase inhibitor multiprotein complex naphthyridine derivative nucleoprotein biochemistry chemical binding human immunodeficiency virus inhibitor protein ultrastructure amino terminal sequence Article carboxy terminal sequence catalysis cryoelectron microscopy drug design drug efficacy drug protein binding drug resistance drug structure enzyme active site human Human immunodeficiency virus infection nonhuman priority journal protein purification protein structure antiviral resistance chemistry drug effect genetics Human immunodeficiency virus virus DNA cell DNA interaction Cryoelectron Microscopy Drug Design Drug Resistance, Viral Heterocyclic Compounds, 4 or More Rings HIV HIV Integrase HIV Integrase Inhibitors Humans Multiprotein Complexes Naphthyridines Nucleoproteins Virus Integration |
| Structural basis of second-generation HIV integrase inhibitor action and viral resistance 期刊论文 , 2020, 卷号: 367, 期号: 6479 作者: Cook N.J.; Li W.; Berta D.; Badaoui M.; Ballandras-Colas A.; Nans A.; Kotecha A.; Rosta E.; Engelman A.N.; Cherepanov P. 收藏  |  浏览/下载:29/0  |  提交时间:2020/07/28 bictegravir dolutegravir lens epithelium derived growth factor magnesium ion bictegravir dolutegravir fused heterocyclic rings glutamine glycine histidine integrase integrase inhibitor magnesium serine acquired immune deficiency syndrome amino acid drug human immunodeficiency virus inhibitor protein ultrastructure virus amino acid substitution amino terminal sequence Article carboxy terminal sequence cryoelectron microscopy DNA binding drug design drug protein binding drug structure enzyme active site gene mutation Human immunodeficiency virus 1 in vitro study molecular dynamics molecular stability nonhuman pharmacophore polarization priority journal protonation virus resistance antiviral resistance chemistry genetics human mutation procedures single molecule imaging Amino Acid Substitution Catalytic Domain Cryoelectron Microscopy Drug Resistance, Viral Glutamine Glycine Heterocyclic Compounds, 3-Ring Heterocyclic Compounds, 4 or More Rings Histidine HIV Integrase HIV Integrase Inhibitors Humans Magnesium Mutation Serine Single Molecule Imaging |
| Ferrocene derivatives as anti-infective agents 期刊论文 COORDINATION CHEMISTRY REVIEWS, 2019, 卷号: 396, 页码: 22-48 作者: Ludwig, Beatrice S.; Correia, Joao D. G.; Kuehn, Fritz E. 收藏  |  浏览/下载:33/0  |  提交时间:2019/11/07 |