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The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 11, 页码: 1671-1682
作者:  Cote, Ila;  Andersen, Melvin E.;  Ankley, Gerald T.;  Barone, Stanley;  Birnbaum, Linda S.;  Boekelheide, Kim;  Bois, FredericY.;  Burgoon, Lyle D.;  Chiu, Weihsueh A.;  Crawford-Brown, Douglas;  Crofton, Kevin M.;  DeVito, Michael;  Devlin, Robert B.;  Edwards, Stephen W.;  Guyton, Kathryn Z.;  Hattis, Dale;  Judson, Richard S.;  Knight, Derek;  Krewski, Daniel;  Lambert, Jason;  Maull, Elizabeth Anne;  Mendrick, Donna;  Paoli, Gregory M.;  Patel, Chirag Jagdish;  Perkins, Edward J.;  Poje, Gerald;  Portier, Christopher J.;  Rusyn, Ivan;  Schulte, Paul A.;  Simeonov, Anton;  Smith, Martyn T.;  Thayer, Kristina A.;  Thomas, Russell S.;  Thomas, Reuben;  Tice, Raymond R.;  Vandenberg, John J.;  Villeneuve, Daniel L.;  Wesselkamper, Scott;  Whelan, Maurice;  Whittaker, Christine;  White, Ronald;  Xia, Menghang;  Yauk, Carole;  Zeise, Lauren;  Zhao, Jay;  DeWoskin, Robert S.
收藏  |  浏览/下载:31/0  |  提交时间:2019/05/04
ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 8, 页码: 1225-1251
作者:  Richard, Ann M.;  Judson, Richard S.;  Houck, Keith A.;  Grulke, Christopher M.;  Volarath, Patra;  Thillainadarajah, Inthirany;  Yang, Chihae;  Rathman, James;  Martin, Matthew T.;  Wambaugh, John F.;  Knudsen, Thomas B.;  Kancherla, Jayaram;  Mansouri, Kamel;  Patlewicz, Grace;  Williams, Antony J.;  Little, Stephen B.;  Crofton, Kevin M.;  Thomas, Russell S.
收藏  |  浏览/下载:34/0  |  提交时间:2019/05/04
Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2016, 卷号: 79, 页码: 12-24
作者:  Shah, Imran;  Liu, Jie;  Judson, Richard S.;  Thomas, Russell S.;  Patlewicz, Grace
收藏  |  浏览/下载:2/0  |  提交时间:2019/05/04
Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 7, 页码: 1050-1061
作者:  Leung, Maxwell C. K.;  Phuong, Jimmy;  Baker, Nancy C.;  Sipes, Nisha S.;  Klinefelter, Gary R.;  Martin, Matthew T.;  McLaurin, Keith W.;  Setzer, R. Woodrow;  Darney, Sally Perreault;  Judson, Richard S.;  Knudsen, Thomas B.
收藏  |  浏览/下载:26/0  |  提交时间:2019/05/04
Using ToxCast (TM) Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 7, 页码: 910-919
作者:  Shah, Imran;  Setzer, R. Woodrow;  Jack, John;  Houck, Keith A.;  Judson, Richard S.;  Knudsen, Thomas B.;  Liu, Jie;  Martin, Matthew T.;  Reif, David M.;  Richard, Ann M.;  Thomas, Russell S.;  Crofton, Kevin M.;  Dix, David J.;  Kavlock, Robert J.
收藏  |  浏览/下载:30/0  |  提交时间:2019/05/04
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 7, 页码: 1023-1033
作者:  Mansouri, Kamel;  Abdelaziz, Ahmed;  Rybacka, Aleksandra;  Roncaglioni, Alessandra;  Tropsha, Alexander;  Varnek, Alexandre;  Zakharov, Alexey;  Worth, Andrew;  Richard, Ann M.;  Grulke, Christopher M.;  Trisciuzzi, Daniela;  Fourches, Denis;  Horvath, Dragos;  Benfenati, Emilio;  Muratov, Eugene;  Wedebye, Eva Bay;  Grisoni, Francesca;  Mangiatordi, Giuseppe F.;  Incisivo, Giuseppina M.;  Hong, Huixiao;  Ng, Hui W.;  Tetko, Igor V.;  Balabin, Ilya;  Kancherla, Jayaram;  Shen, Jie;  Burton, Julien;  Nicklaus, Marc;  Cassotti, Matteo;  Nikolov, Nikolai G.;  Nicolotti, Orazio;  Andersson, Patrik L.;  Zang, Qingda;  Politi, Regina;  Beger, Richard D.;  Todeschini, Roberto;  Huang, Ruili;  Farag, Sherif;  Rosenberg, Sine A.;  Slavov, Svetoslav;  Hu, Xin;  Judson, Richard S.
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/04
Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 6, 页码: 697-702
作者:  Egeghy, Peter P.;  Sheldon, Linda S.;  Isaacs, Kristin K.;  Ozkaynak, Haluk;  Goldsmith, Michael-Rock;  Wambaugh, John F.;  Judson, Richard S.;  Buckley, Timothy J.
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/04
Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 151, 期号: 1, 页码: 160-180
作者:  Friedman, Katie Paul;  Watt, Eric D.;  Hornung, Michael W.;  Hedge, Joan M.;  Judson, Richard S.;  Crofton, Kevin M.;  Houck, Keith A.;  Simmons, Steven O.
收藏  |  浏览/下载:25/0  |  提交时间:2019/05/04
Coupled molecular design diagrams to guide safer chemical design with reduced likelihood of perturbing the NRF2-ARE antioxidant pathway and inducing cytotoxicity 期刊论文
GREEN CHEMISTRY, 2016, 卷号: 18, 期号: 23, 页码: 6387-6394
作者:  Shen, Longzhu Q.;  Melnikov, Fjodor;  Roethle, John;  Gudibanda, Aditya;  Judson, Richard S.;  Zimmerman, Julie B.;  Anastas, Paul T.
收藏  |  浏览/下载:36/0  |  提交时间:2019/05/04
Probabilistic diagram for designing chemicals with reduced potency to incur cytotoxicity 期刊论文
GREEN CHEMISTRY, 2016, 卷号: 18, 期号: 16, 页码: 4461-4467
作者:  Shen, Longzhu Q.;  Judson, Richard S.;  Melnikov, Fjodor;  Roethle, John;  Gudibanda, Aditya;  Zimmerman, Julie B.;  Anastas, Paul T.
收藏  |  浏览/下载:18/0  |  提交时间:2019/05/04