The environment is indeed in grave health and urgent action is desperately needed. But there is genuine optimism that solutions to some of the largest environmental challenges may finally be at hand.
But a rapidly growing collective of engineers, scientists, activists and entrepreneurs are delivering some of the biggest gains in environmental remediation in recent decades by blurring the lines between physical, biological and digital sciences. We call ourselves synthetic biologists.
I have extensively contributed to research, education, commercialization and regulation of synthetic biology, including as the founder of Metabolik Technologies, an environmental biotechnology venture, that commercialized a first-of-its-kind, low-energy, low-cost and sustainable solution to decontaminate oilsands tailings ponds.
A quick guide to synthetic biology
The underlying premise of synthetic biology is as simple as it is elegant: Nature assembles, dismantles and recycles molecules in the cleanest and most efficient manner imaginable. The unique instructions required to achieve these tasks are found in DNA.
Synthetic biologists investigate natural systems in order to understand these remarkable processes and then use lab-synthesized DNA to reprogram them to perform new tasks or existing tasks more efficiently.
Importantly, many of the protagonists and influencers of synthetic biology are the millennials and zoomers who were raised on a steady diet of Saturday morning cartoons.
Crucially, the successes of synthetic biology in the sphere of environmental remediation have not been one-off demonstrations in academic laboratories. They have been proven in the field at sizeable scales and they have taken large bites out of some of the greatest environmental challenges in the world.
These microbes do not merely survive, but thrive in the contaminated water. They sense, ingest and metabolize the toxic compounds in the water, albeit at very slow rates. My team at the University of British Columbia and our colleagues at Allonnia isolated and studied the genomics of these unique creatures and, in collaboration with Ginkgo Bioworks, are now increasing their appetite for and metabolism of the toxic compounds.
After validating the performance of the micro-organisms in the field, the UBC-Allonnia team designed some of the largest treatment systems of their kind to achieve the rates and scales needed to remediate the water within the timeline prescribed in Alberta's Tailings Management Framework.
We will test our treatment system at the tailings ponds in early 2022 to fine-tune the micro-organisms and the reactors, and assess the risks. Some of these risks include the inefficacy or higher than expected costs of the technology, the potential damage the microbes may cause to the ecosystem and whether regulators and shareholders are comfortable with deploying engineered micro-organisms in the environment.
This small group of synthetic biologists succeeded thanks to the ingenuity of the approach and new models of collaboration. The team also involved oilsands operators, engineering design firms, contract manufacturing companies and regulatory experts who were able to leverage each partner's strengths to reduce the time, expense and uncertainty of developing a practical solution.
The fun has only just begun
Synthetic biologists are only getting started and have now set their sights on a number of similarly large problems. One, in particular, has significant implications for our electric future.
Mining giant @TeckResources is contributing more than $1.5 million to reclamation efforts at the infamous Tulsequah Chief mine, which it owned previously and abandoned in 1957. #bcpoli Via @writermjshttps://t.co/UcOpvPpouv
Mining is wasteful and unsustainable, and the industry is in desperate need of effective solutions to treat its large bodies of waste. My new start-up company ArqMetal is developing microbial solutions to do away with tailings ponds entirely. If we and others like us are successful, we will eliminate waste, deliver decarbonization, preserve biodiversity, generate employment and achieve equitable social development. Isn't this what the architects of the Green New Deal had in mind?
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How engineered bacteria could clean up oilsands pollution and mining waste (2021, June 23)
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